dichlorvos induced autoimmune hepatitis: a case report and review of literature

introduction drug-induced liver injury is a frequent cause of hepatic dysfunction. several drugs have been identified to cause autoimmune hepatitis (aih). environmental chemicals are capable of triggering a certain degree of liver injury. however, toxin induced aih is rare. conclusions chronic (long-term) exposures to dichlorvos can lead to aih. a detailed inquiry of medical history and liver biopsy are necessary for the diagnosis of toxin-induced aih. corticosteroid therapy is associated with favorable evolution. case presentation we reported a woman with chronic (long-term) exposures to dichlorvos, which resulted in liver injury and cirrhosis. she was diagnosed after a second liver biopsy, which was correlated with laboratory findings. at the same time, she experienced hepatic cortical blindness during her first admission.